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Encephalomyocarditis virus antibodies in sera from apparently normal pigs
The Veterinary Record
|March 19, 1977
Summary
Antibodies neutralizing encephalomyocarditis virus are present in over 28% of normal British pigs. This neutralizing activity is linked to various antibody sizes, indicating a common immune response.
Area of Science:
- Veterinary Virology
- Immunology
Background:
- Encephalomyocarditis virus (EMCV) poses a threat to swine health.
- Understanding natural immunity in pig populations is crucial for disease control.
Purpose of the Study:
- To investigate the prevalence and characteristics of antibodies targeting encephalomyocarditis virus in a normal pig population in Britain.
Main Methods:
- Serum samples from normal pigs in Britain were collected.
- Antibody presence was detected using neutralization and precipitation assays.
- Antibody size classes associated with neutralizing activity were analyzed.
Main Results:
- Antibodies capable of neutralizing and precipitating encephalomyocarditis virus were identified in over 28% of the pigs studied.
- Neutralizing activity was observed across multiple antibody size classes, suggesting a diverse immune response.
Conclusions:
- A significant proportion of normal British pigs possess antibodies against encephalomyocarditis virus.
- The presence of these antibodies, associated with various size classes, indicates natural exposure and a potential level of immunity within the pig population.