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Related Concept Videos

Skeletal Muscle Anatomy00:55

Skeletal Muscle Anatomy

Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
Gross Anatomy of Skeletal Muscles01:12

Gross Anatomy of Skeletal Muscles

The connective tissues play a significant role in arranging the muscle fibers into a hierarchical structure that forms a complete muscle. Consider a muscle like the bicep brachii, commonly called the bicep. This muscle comprises thousands of muscle fibers enclosed by a protective layer of connective tissue called the endomysium. The endomysium is primarily composed of reticular fibers, a type of thin collagen fiber. It allows the exchange of nutrients and waste products at the fiber level,...
Muscle Contraction01:15

Muscle Contraction

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Related Experiment Video

Updated: Jun 21, 2026

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
07:30

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

Published on: January 13, 2022

An artificial tendon with durable muscle interface.

Alan Melvin1, Alan Litsky, Joel Mayerson

  • 1Surgical Energetics, Inc., Cincinnati, Ohio 45219-2374, USA.

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
|July 30, 2009
PubMed
Summary
This summary is machine-generated.

The novel OrthoCoupler device securely attaches contracting muscles to bone anchors, outperforming traditional sutures in biomechanical tests. This innovative orthopedic solution offers enhanced strength and durability for various surgical reconstructions.

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A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
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Published on: December 10, 2021

Ex vivo Mechanical Loading of Tendon
11:36

Ex vivo Mechanical Loading of Tendon

Published on: May 28, 2007

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Last Updated: Jun 21, 2026

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
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A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
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Ex vivo Mechanical Loading of Tendon
11:36

Ex vivo Mechanical Loading of Tendon

Published on: May 28, 2007

Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Musculoskeletal Research

Background:

  • A critical need exists for reliable methods to fix forcefully contracting muscles to bone anchors or prostheses in orthopedics.
  • Existing methods may not provide sufficient strength or durability for certain reconstructive procedures.

Purpose of the Study:

  • To evaluate the in vitro and in vivo performance of the novel OrthoCoupler device for muscle-to-bone reattachment.
  • To compare the OrthoCoupler's strength and durability against traditional suture techniques.

Main Methods:

  • In vitro fatigue testing of 40 OrthoCoupler samples across 10 load levels.
  • In vivo study in goats, reattaching semitendinosus tendons using OrthoCoupler versus Krackow stitch sutures.
  • Biomechanical and histological analysis of specimens 60 days post-surgery.

Main Results:

  • In vitro fatigue testing demonstrated OrthoCoupler strength significantly exceeding the muscle's contractile force.
  • In vivo strength testing showed OrthoCoupler failure at 298 +/- 111.3 N after muscle tear, compared to suture pull-out at 120.5 +/- 68.3 N (p < 0.0003).
  • The OrthoCoupler maintained integrity even when the healed muscle-tendon unit failed.

Conclusions:

  • The OrthoCoupler provides superior biomechanical strength and reliability compared to standard suture techniques for tendon reattachment.
  • This device shows significant potential for improving outcomes in orthopedic applications including oncology, revision arthroplasty, tendon transfers, and sports injury reconstruction.