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Updated: Jun 21, 2026
07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Gastrointestinal symptom improvement after Roux-en-Y gastric bypass: long-term analysis
Naveen Ballem1, Kishore Yellumahanthi, Matthew Wolfe
1Director of Bariatric Surgery, Clara Maass Medical Center, Saint Barnabas Health Care System, Belleville, New Jersey, USA. nballem@hotmail.com
Summary
Roux-en-Y gastric bypass (RYGB) significantly improves gastrointestinal symptoms in obese patients. These improvements are substantial and durable long-term, enhancing patient well-being after bariatric surgery.
Area of Science:
- Gastroenterology
- Bariatric Surgery
- Obesity Medicine
Background:
- Obese individuals experience distinct gastrointestinal (GI) symptoms compared to non-obese individuals.
- Limited data exist on GI symptom changes before and after Roux-en-Y gastric bypass (RYGB).
Purpose of the Study:
- To quantify GI symptoms in obese patients.
- To assess the changes in GI symptoms following laparoscopic RYGB.
Main Methods:
- Prospective administration of 1724 GI symptom surveys to 763 patients undergoing laparoscopic RYGB.
- Symptom severity rated on a 0-100mm Likert scale preoperatively and annually post-surgery.
- Data analyzed and presented as mean ± standard error of the mean.
Main Results:
- Preoperative symptoms included heartburn (41.0±0.8), increased flatus (38.9±0.8), and difficulty sleeping (42.0±1.1).
- Significant improvement (P < .05) in 99.5%, 84.2%, 68.4%, 57.9%, and 47.4% of symptoms at 1, 2, 3, 4, and 5 years post-RYGB, respectively.
- No adverse effects on measured parameters were observed.
Conclusions:
- Laparoscopic RYGB leads to significant and durable improvements in GI symptoms for morbidly obese patients.
- The procedure enhances quality of life without negative impacts on other health parameters.
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