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Updated: Jun 21, 2026

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration
Published on: August 7, 2019
[Filarial infestation in patients emanating from endemic area. 14 cases series presentation]
M Rivera Cuello1, E Núñez Cuadros, A Medina Claros
1Unidad de Pediatría Tropical, Servicio de Pediatría, Hospital Carlos III, Madrid, España. ronijerez@hotmail.com
Introduction:
The migration causes the emergence of new diseases in our environment. One of them is the filariosis which, due to the biologic cycle peculiarity, it's weird its appearance in pediatrics. This studio accomplishes a review of all the filariosis cases diagnosed the last years in an Unit specialized in Tropical Pediatrics Diseases.
Material And Methods:
Retrospective analysis comprising 14 patients than were diagnosed with filariosis from 1995 to 2007 in the Pediatrics Unit of Carlos III Hospital (Madrid). They have been analyzed several variables to cope with clinic-epidemiological, therapeutics and evolutional characteristics.
Results:
All patients in the study came from Equatorial Guinea, their ages were between 3 and 15 years old. The isolated species were: 6 cases with O. volvulus, 8 with M. perstans and 2 with Loa-loa. The pruritus was the main symptom in the 71% of the cases. The eosinophilia was detected in the 78% of the patients, and the Loa-loa was the specie with higher figures. The 85% of the patients showed co-parasitation, being the intestinal the most frequent. The diagnostics was established by epidermic biopsy, microfilaremia detection, direct visualization and serology. The utilized drugs were: Mebendazole for the cases with M. perstans and Ivermectin or Dietylcarbamazine for the rest of the species. One child showed mixed filariosis. The cure was successful in the 8 cases that could be followed up.
Conclusions:
We consider essential to execute a filariosis screening to every patient emanating from endemic area, especially to those with eosinophilia. The diagnostic in the childhood, even though it's difficult, it allows the prevention of the disease development, serious complications as blindness and break the parasite life cycle.
Insights
Filariosis in children, though rare, requires prompt diagnosis and treatment. Early screening of pediatric patients from endemic areas is crucial for preventing severe complications like blindness and interrupting disease transmission.
Area of Science:
- Tropical medicine
- Pediatric infectious diseases
- Parasitology
Context:
- Migration patterns facilitate the emergence of novel infectious diseases.
- Filariosis presents unique challenges in pediatric cases due to its peculiar biological cycle.
- This study reviews filariosis cases diagnosed in a specialized Tropical Pediatrics Diseases Unit.
Purpose:
- To review clinical-epidemiological, therapeutic, and evolutionary characteristics of filariosis in pediatric patients.
- To analyze diagnosed filariosis cases in children over a 12-year period.
- To highlight the importance of early diagnosis and screening for filariosis in children.
Summary:
- A retrospective analysis of 14 pediatric filariosis cases (1995-2007) from Equatorial Guinea revealed common species like *O. volvulus*, *M. perstans*, and *Loa-loa*.
- Pruritus and eosinophilia were prevalent symptoms, with co-parasitation occurring in 85% of cases. Diagnosis involved biopsy, microfilaremia detection, visualization, and serology.
- Treatment varied by species, including Mebendazole, Ivermectin, and Diethylcarbamazine, with successful outcomes in followed-up cases.
Impact:
- Highlights the necessity of filariosis screening for children from endemic regions, particularly those with eosinophilia.
- Emphasizes that early childhood diagnosis, despite challenges, aids in preventing severe sequelae such as blindness.
- Underscores the role of timely diagnosis in breaking the parasite's life cycle and preventing disease progression.
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