Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Valve-Specific Comparative Effectiveness of Direct Oral Anticoagulants Versus Vitamin K Antagonists After Surgical Valve Procedures in Atrial Fibrillation: A Systematic Review and Meta-Analysis.

Cardiology in review·2026
Same author

Interfacial Control in Cu-MXene Hybrids Enables Selective NOx-to-NH<sub>3</sub> Electroconversion: A Critical Review.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

First-Principles Design of Room Temperature Ferromagnetic Metallic Rare-Earth Zintl Compounds AB<sub>2</sub>C<sub>2</sub> (A = Ce, Pr, Nd; B = Li; C = Sb) for Next-Generation Spintronic and Magneto-Electronic Applications.

ChemistryOpen·2026
Same author

From polyethylene terephthalate waste to a multilayer MOF: a sustainable strategy for enhanced supercapacitor performance.

RSC advances·2026
Same author

Evaluating Diagnostic Capability of Computed Tomography and Role of Bronchoscopy in Admitted Cases With Pulmonary Diseases.

Saudi medical journal·2026
Same author

Device-based therapies for cardiorenal syndrome: A comprehensive, mechanism-driven framework for next-generation decongestion.

European journal of internal medicine·2026

Related Experiment Video

Updated: Jun 21, 2026

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Diastolic dysfunction and COPD exacerbation.

Ghassan H Abusaid1, Alejandro Barbagelata, Enrique Tuero

  • 1University of Texas, Galveston, TX 77555, USA.

Postgraduate Medicine
|July 31, 2009
PubMed
Summary
This summary is machine-generated.

Patients with Chronic Obstructive Pulmonary Disease (COPD) and diastolic dysfunction (DD) experience longer hospital stays and more frequent exacerbations requiring admission. This highlights DD as a significant factor in COPD management.

More Related Videos

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
05:34

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Related Experiment Videos

Last Updated: Jun 21, 2026

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
05:34

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Area of Science:

  • Cardiology
  • Pulmonology
  • Internal Medicine

Background:

  • Chronic Obstructive Pulmonary Disease (COPD) exacerbations are a leading cause of hospital admissions.
  • A significant portion of COPD exacerbations lack a clear etiological cause.
  • Diastolic dysfunction (DD) is a potential, understudied factor in unexplained COPD exacerbations.

Purpose of the Study:

  • To investigate the association between diastolic dysfunction (DD) and hospitalization outcomes in patients with COPD exacerbations.
  • To determine if DD correlates with increased length of hospital stay and exacerbation frequency in COPD patients.

Main Methods:

  • Retrospective chart review of 139 patients hospitalized for acute COPD exacerbation.
  • Categorization of patients into groups with and without diastolic dysfunction (DD) based on echocardiogram findings.
  • Analysis of hospitalization duration and exacerbation rates per patient-year.

Main Results:

  • Patients with DD exhibited a significantly longer mean length of stay (4.02 days) compared to those without DD (3.24 days).
  • The incidence of hospitalizing exacerbations was higher in the DD group (1.28 per patient-year) versus the normal diastolic function group (0.67 per patient-year).
  • Statistical significance was observed for both length of stay (P = 0.005) and exacerbation frequency (P = 0.0067).

Conclusions:

  • Diastolic dysfunction (DD) is associated with prolonged and more frequent hospitalizations in COPD patients.
  • DD may serve as a marker for increased left ventricular filling pressures, contributing to COPD exacerbation severity.
  • Identifying DD in COPD patients could inform strategies to reduce hospital admissions and improve patient outcomes.