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A computer-based matrix for rapid calculation of pulmonary hemodynamic parameters in congenital heart disease
Antonio Augusto Lopes1, Rogério Dos Anjos Miranda, Rilvani Cavalcante Gonçalves
1Department of Pediatric Cardiology and Adult Congenital Heart Disease, Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, Brazil. aablopes@usp.br
Background:
In patients with congenital heart disease undergoing cardiac catheterization for hemodynamic purposes, parameter estimation by the indirect Fick method using a single predicted value of oxygen consumption has been a matter of criticism.
Objective:
We developed a computer-based routine for rapid estimation of replicate hemodynamic parameters using multiple predicted values of oxygen consumption.
Materials And Methods:
Using Microsoft® Excel facilities, we constructed a matrix containing 5 models (equations) for prediction of oxygen consumption, and all additional formulas needed to obtain replicate estimates of hemodynamic parameters.
Results:
By entering data from 65 patients with ventricular septal defects, aged 1 month to 8 years, it was possible to obtain multiple predictions for oxygen consumption, with clear between-age groups (P <.001) and between-methods (P <.001) differences. Using these predictions in the individual patient, it was possible to obtain the upper and lower limits of a likely range for any given parameter, which made estimation more realistic.
Conclusion:
The organized matrix allows for rapid obtainment of replicate parameter estimates, without error due to exhaustive calculations.
