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Updated: Jun 21, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Studies on chemical constituents of Ligularia altaica]
Chao-Feng Zhang1, Qiong Wang, Mian Zhang
1Key Laboratory of Modern Chinese Medicines of Ministry of Education/Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. inchaofeng@126.com
Objective:
To study the chemical constituents of Lighularia altaica.
Methods:
Various chromatographic techniques were used to isolate and purify the chemical compounds, their structure were elucidated by means of mass, physico-chemical properties and NMR spectral data.
Results:
Nine compounds were obtained as: lupeol (1), oleanolic acid (2), 3beta, 16beta-dihydroxy-12-oleanen-28-al (3), ergosterol peroxide (4), stigmasta-7-en-ol (5), 11-hydroxy-10,11-dihydro-euparin (6), 5-hydroxybenzofuran-2(3H) -one- (7), except for beta-sitosterol (8) and daucostrol (9).
Conclusion:
Compounds 3 - 7 are isolated for the first time from this genus, the other compounds are obtained from this plant for the first time.
