Related Experiment Video
Updated: Jun 21, 2026
06:59
Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Congenital Anterior Staphyloma
Journal of Pediatric Ophthalmology and Strabismus
|August 4, 2009
Summary
Congenital anterior staphyloma, a rare eye condition, involves corneal protrusion. Surgical corneoscleral transplant offers a viable cosmetic alternative to enucleation for affected infants.
Area of Science:
- Ophthalmology
- Developmental Biology
- Surgical Reconstruction
Background:
- Staphyloma of the anterior eye segment is a rare developmental abnormality.
- Embryogenesis is implicated as the primary cause based on histopathologic and electron microscopic studies.
Purpose of the Study:
- To describe a case of congenital anterior staphyloma in a pediatric patient.
- To evaluate the efficacy of corneoscleral transplant as a reconstructive option.
Main Methods:
- Surgical removal of the congenital anterior staphyloma.
- Reconstruction of the eyeball using a total corneoscleral transplant.
- Clinical and histopathologic examination of the affected eye.
Main Results:
- Successful surgical intervention for a 1-year-old girl with corneal protrusion.
- Clinical and histopathologic findings confirmed congenital anterior staphyloma.
- The corneoscleral transplant provided a favorable cosmetic outcome.
Conclusions:
- Congenital anterior staphyloma requires specialized surgical management.
- Total corneoscleral transplant is a successful reconstructive technique for anterior staphyloma.
- This surgical approach offers a good cosmetic alternative to enucleation.
Related Concept Videos
01:29Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
01:22Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:26Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...