Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 21, 2026

Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture
10:08

Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture

Published on: October 21, 2009

Electrospun scaffolds for stem cell engineering.

Shawn H Lim1, Hai-Quan Mao

  • 1Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA. shlim@jhu.edu

Advanced Drug Delivery Reviews
|August 4, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

N<sup>4</sup>-Acetylcytidine enhances synthetic mRNA translation yield and fidelity.

Nature·2026
Same author

FALCON: Closed-Loop Multi-Objective Optimization of Lipid Nanoparticles for Cell-Selective mRNA Delivery.

bioRxiv : the preprint server for biology·2026
Same author

Evaluation of immunogenicity and efficacy of a Plasmodium vivax nanoparticle vaccine in mice.

Vaccine·2026
Same author

Oversimplified immunology is holding biomaterials back.

Nature reviews bioengineering·2026
Same author

Lipid nanoparticle composition directs systemic trafficking and tissue-specific T cell immunity after intramuscular injection.

Nature biomedical engineering·2026
Same author

Controlled release of rhBMP-2 from nanoparticle-loaded biomimetic graft promotes bone regeneration in a rat spinal fusion model.

Biomaterials advances·2026
Same journal

Silicone oil in protein drug products and its implications for formulation stability.

Advanced drug delivery reviews·2026
Same journal

Targeted delivery of proteolysis-targeting chimeras (PROTAC) and molecular glue degraders (MGD).

Advanced drug delivery reviews·2026
Same journal

Lysosome-targeting degrader delivery system: from formulation design to biomedical applications.

Advanced drug delivery reviews·2026
Same journal

Anti-PEG antibodies in nanomedicine: Mechanisms, risks, and opportunities.

Advanced drug delivery reviews·2026
Same journal

Optimizing macrophage-targeted intracellular delivery systems for safe and effective immunotherapies.

Advanced drug delivery reviews·2026
Same journal

Light-controlled CRISPR-dCas9 epigenome editing: advanced drug-delivery strategies and oncology applications.

Advanced drug delivery reviews·2026
See all related articles

Synthetic scaffolds mimic the natural cell environment, enhancing stem cell potential for tissue repair. This technology offers a versatile platform for regenerative medicine applications.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Stem Cell Biology

Background:

  • Stem cells are influenced by their extracellular microenvironment.
  • Synthetic scaffolds offer a controlled environment for stem cell manipulation.
  • Regenerative medicine seeks to harness stem cell potential for tissue repair.

Purpose of the Study:

  • To investigate the use of electrospun fibrous scaffolds for stem cell applications.
  • To demonstrate the feasibility of presenting integrated topographical and biochemical signals.
  • To explore the potential of these scaffolds for functional tissue repair and regeneration.

Main Methods:

  • Fabrication of electrospun fibrous scaffolds with controlled structure and porosity.
  • Functional modification of scaffolds to enhance stem cell survival, proliferation, and differentiation.

More Related Videos

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells
08:03

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells

Published on: June 18, 2014

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization
09:32

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization

Published on: April 19, 2015

Related Experiment Videos

Last Updated: Jun 21, 2026

Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture
10:08

Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture

Published on: October 21, 2009

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells
08:03

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells

Published on: June 18, 2014

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization
09:32

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization

Published on: April 19, 2015

  • Presentation of integrated topographical and biochemical cues to stem cells.

    • Main Results:

    • Scaffolds successfully mimicked extracellular matrix topography.
    • Scaffolds supported stem cell survival and proliferation.
    • Integrated signals on scaffolds demonstrated feasibility for stem cell manipulation.

    Conclusions:

    • Electrospun fibrous scaffolds provide a versatile platform for regenerative medicine.
    • These scaffolds can be tailored to present specific signals for stem cell manipulation.
    • Future applications include tissue repair using human embryonic and induced pluripotent stem cells.