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Updated: Jun 21, 2026
Integrating Augmented Reality Tools in Breast Cancer Related Lymphedema Prognostication and Diagnosis
Published on: February 6, 2020
The impact of margin status in breast-conserving therapy for lobular carcinoma is age related
J J Jobsen1, S Riemersma, J van der Palen
1Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, The Netherlands. j.jobsen@mst.nl
Purpose:
The aim is to look at the impact of margin status and outcome of invasive lobular carcinoma (ILC) treated with breast-conserving therapy (BCT).
Methods:
This manuscript describes an analysis on 330 BCT in 318 patients with ILC.
Results:
The 12-year local relapse free survival (LRFS) is 89%. In multivariate analysis, positive margin status, age>50 years, contra lateral breast cancer, and adjuvant systemic therapy were significant predictors of local relapse free survival. In a separate analysis limited to a positive margin for invasive carcinoma or carcinoma in situ, only a positive margin for invasive carcinoma was a significant predictor of local relapse free survival. This was limited to women
Conclusions:
Positive margins for invasive carcinoma seem to be a strong predictor for local recurrence in particular for women
