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Related Concept Videos

Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results from...
Huntington Disease l: Introduction01:21

Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

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Related Experiment Video

Updated: Jun 21, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

One disease, two lives.

Alexa G Visco1, Lara C Meyer, Shuo Xi

  • 1Fletcher Allen Health Care, Burlington, VT, USA. alexa.visco@vtmednet.org

Clinical Journal of Oncology Nursing
|August 4, 2009
PubMed
Summary
This summary is machine-generated.

Breast cancer in pregnancy is rising due to delayed childbirth. Chemotherapy during pregnancy may be safe for mother and fetus, with important nursing implications.

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Last Updated: Jun 21, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

Area of Science:

  • Oncology
  • Maternal-Fetal Medicine
  • Perinatal Care

Background:

  • Increasing maternal age at childbirth is linked to a rise in breast cancer incidence during pregnancy.
  • Breast cancer affects approximately 1 in 3,000 pregnancies, with about 10% of young women under 40 diagnosed being pregnant.
  • Historically, obstetric and oncology care for pregnant patients with cancer have been separate clinical domains.

Observation:

  • Case studies indicate that chemotherapy administration during the second and third trimesters of pregnancy may be safe for both the mother and the developing fetus.
  • Three case studies detail the clinical management and outcomes of pregnant women undergoing cancer treatment.
  • The study explores the potential effects of in utero chemotherapy exposure on infant development and associated nursing care considerations.

Findings:

  • Chemotherapy during pregnancy, specifically in the second and third trimesters, shows potential safety for maternal and fetal outcomes.
  • Detailed case studies provide insights into managing breast cancer in pregnant individuals.
  • Infant outcomes following in utero chemotherapy exposure are examined, highlighting specific nursing care needs.

Implications:

  • This research highlights the feasibility and safety considerations of treating breast cancer during pregnancy.
  • It underscores the need for multidisciplinary collaboration between oncology and obstetrics/neonatal care teams.
  • Findings inform clinical practice regarding chemotherapy protocols, patient counseling, and specialized nursing care for pregnant cancer patients and their infants.