Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pneumocephalus in pneumococcal meningitis.

Acta neurologica Belgica·2025
Same author

Impact of deep learning image reconstruction on volumetric accuracy and image quality of pulmonary nodules with different morphologies in low-dose CT.

Cancer imaging : the official publication of the International Cancer Imaging Society·2024
Same author

Two Cases of Post-Traumatic Mucormycosis due to <i>Mucor circinelloides</i>: Salvage Therapy with a Combination of Adjunctive Therapies.

Case reports in infectious diseases·2022
Same author

Reproducible determination of transpulmonary pressures.

MethodsX·2022
Same author

COVID-19 pneumonia imaging follow-up: when and how? A proposition from ESTI and ESR.

European radiology·2021
Same author

PULMONARY NODULE DETECTION IN CHEST CT USING A DEEP LEARNING-BASED RECONSTRUCTION ALGORITHM.

Radiation protection dosimetry·2021
Same journal

Beyond the 5th percentile: rethinking diagnostic thresholds in pulmonary function testing.

The European respiratory journal·2026
Same journal

A Transcriptomic Atlas of Chronic Lung Allograft Dysfunction.

The European respiratory journal·2026
Same journal

Risk of cancer and mortality in patients with interstitial lung diseases: Danish cohort study.

The European respiratory journal·2026
Same journal

Proposing a minimal important difference in NTproBNP in pulmonary arterial hypertension.

The European respiratory journal·2026
Same journal

Unlocking growth potential: Ivacaftor therapy and developmental gains in lung and height in a cohort study of children and young adults with cystic fibrosis.

The European respiratory journal·2026
Same journal

Decoding the Lymphangioleiomyomatosis (LAM) Niche Microenvironment <i>via</i> Integrative Analysis of Single Cell Multiomics and Spatial Transcriptomics.

The European respiratory journal·2026
See all related articles

Related Experiment Video

Updated: Jun 21, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Nonthrombotic pulmonary embolism.

P G Jorens1, E Van Marck, A Snoeckx

  • 1Department of Critical Care Medicine, ZA, Antwerp University Hospital, University of Antwerp, Edegem, Belgium. Philippe.Jorens@uza.be

The European Respiratory Journal
|August 4, 2009
PubMed
Summary
This summary is machine-generated.

Nonthrombotic pulmonary embolism (NTPE), caused by various substances like cells, bacteria, or gas, presents a diagnostic challenge with diverse symptoms and requires increased awareness. Early recognition and understanding of its complex pathogenesis are crucial for effective management.

More Related Videos

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
08:02

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

Related Experiment Videos

Last Updated: Jun 21, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
08:02

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

Area of Science:

  • Pulmonary Medicine
  • Pathology
  • Radiology

Background:

  • Nonthrombotic pulmonary embolism (NTPE) involves emboli of diverse materials, not just blood clots.
  • NTPE pathogenesis is complex, involving more than simple mechanical obstruction and potentially causing severe inflammation.

Purpose of the Study:

  • To detail the clinical signs, pathogenesis, diagnosis, and treatment of various NTPE subtypes.
  • To highlight the diagnostic challenges and atypical presentations of NTPE.
  • To familiarize readers with the radiological features of NTPE.

Main Methods:

  • Review of clinical signs, pathogenesis, and diagnostic approaches for NTPE subtypes.
  • Emphasis on pathological findings, including lung biopsies and bronchoalveolar lavage analysis.
  • Description of atypical radiological findings on thin-section computed tomography.

Main Results:

  • NTPE presents with diverse and often overlooked clinical signs, ranging from acute respiratory distress syndrome to chronic findings.
  • Diagnosis frequently relies on pathological examination and may involve specialized tests like pulmonary artery blood aspiration or cell staining.
  • Radiological findings can include "tree-in-bud" patterns and micronodules, aiding in diagnosis.

Conclusions:

  • NTPE is an underestimated cause of acute and chronic pulmonary hypertension.
  • Increased awareness of NTPE is necessary due to its diagnostic complexity and potential severity.
  • Despite extensive descriptions, well-designed therapeutic trials for NTPE subsets are lacking.