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[Seven-weeks cervical pregnancy treated successfully with methotrexate - a case report]
Anita Olejek1, Stanisław Horak, Jacek Zamłyński
1Katedra i Klinika Ginekologii, Połoznictwa i Ginekologii Onkologicznej, ul. Batorego15, 41-902 Bytom.
Summary
This case study shows successful treatment of a 7-week cervical pregnancy in a teenager using methotrexate (MTX). This approach preserved the patient's uterus and fertility, offering a safe alternative for young women.
Area of Science:
- Reproductive Endocrinology
- Gynecologic Oncology
- Maternal-Fetal Medicine
Background:
- Cervical pregnancy is a rare form of ectopic pregnancy.
- Treatment options for cervical pregnancy often involve surgical intervention, potentially impacting fertility.
Observation:
- A 16-year-old nulliparous female presented with vaginal bleeding and abdominal pain, diagnosed with a 7-week cervical pregnancy.
- Initial beta-human chorionic gonadotropin (β-hCG) levels were 2.65 IU/ml, with ultrasound revealing a cervical gestational sac without fetal heartbeat.
Findings:
- The patient received two intravenous doses of methotrexate (MTX): 50 mg initially, followed by 25 mg due to persistent ultrasound findings.
- β-hCG levels decreased significantly from 2.65 IU/ml to 0.0485 IU/ml by day 10.
- Ultrasound confirmed resolution of the cervical pregnancy, and subsequent curettage was uncomplicated.
Implications:
- Methotrexate is a safe and effective treatment for cervical pregnancy in adolescents.
- This medical management preserves uterine integrity and fertility in young nulliparous women.
- This case highlights a potentially viable, fertility-sparing alternative to surgery for cervical pregnancy in teenagers.
