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Updated: Jun 21, 2026

Polymer Microarrays for High Throughput Discovery of Biomaterials
Published on: January 25, 2012
Exploration of polymethacrylate structure-property correlations: Advances towards combinatorial and high-throughput
Paul F Holmes1, Mike Bohrer, Joachim Kohn
1Department of Chemistry and Chemical Biology and The New Jersey Center for Biomaterials, 145 Bevier Road, Rutgers-The State University of New Jersey, Piscataway, NJ 08854.
Abstract:
In this review, we discuss the synthesis, characterization, physical properties, and applications of polymethacrylates and describe physical and biological structure-property correlations relevant to many high performance applications. We also track the advancement of material-property space from the 'traditional' mode of materials design to the emerging, state-of-the-art combinatorial and in silico methods. Particularly, this article places emphasis on recent advances in the automated combinatorial synthesis and development of high-throughput characterization methods. As a future perspective, we believe that the realization of combinatorial, high-throughput, and computational methods will allow for the rapid exploration of a vast polymethacrylate library property space.
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