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Updated: Jun 21, 2026

Identifying Protein-protein Interaction Sites Using Peptide Arrays

Identifying Protein-protein Interaction Sites Using Peptide Arrays

Published on: November 18, 2014

Web-based design of peptide microarrays using microPepArray Pro.

Tongbin Li¹, Zhixiang Zuo, Qi Zhu

¹Department of Neuroscience, University of Minnesota, Minneapolis, MN, USA.

Methods in Molecular Biology (Clifton, N.J.)

|August 4, 2009

Summary

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Peptide microarrays are powerful tools for protein analysis. A new web-based program, microPepArray Pro, simplifies the complex design process for these peptide arrays, enhancing research capabilities.

Area of Science:

Biotechnology
Bioinformatics
Proteomics

Background:

Peptide microarrays are emerging as crucial tools for high-throughput protein analysis, similar to DNA arrays in genomics.
Current technologies enable flexible synthesis of high-density peptide arrays for specific applications like phosphopeptide analysis.
Developing robust computational and informatics resources is essential for maximizing the potential of peptide array technology.

Purpose of the Study:

To introduce microPepArray Pro, a versatile web-based program designed for peptide array design.
To address the complexity of peptide array design compared to DNA arrays.
To provide researchers with enhanced control and flexibility in designing peptide arrays for diverse applications.

Main Methods:

Development of a web-based, general-purpose peptide array design program.

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Last Updated: Jun 21, 2026

Identifying Protein-protein Interaction Sites Using Peptide Arrays

Identifying Protein-protein Interaction Sites Using Peptide Arrays

Published on: November 18, 2014

Analysis of Histone Antibody Specificity with Peptide Microarrays

Analysis of Histone Antibody Specificity with Peptide Microarrays

Published on: August 1, 2017

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Published on: January 7, 2019

Implementation of strong content design capabilities with maximized user control.

Designing for a variety of peptide array configurations and application needs.

Main Results:

microPepArray Pro offers a user-friendly interface for designing peptide arrays.
The program supports diverse design tasks and various array configurations.
microPepArray Pro is highly expandable, allowing for the addition of new functionalities.

Conclusions:

microPepArray Pro significantly simplifies the complex design of peptide arrays.
The program empowers researchers by providing flexibility and control in experimental design.
This tool is expected to foster broader adoption and application of peptide array technology in research.