Related Experiment Video
Updated: Jun 21, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
Published on: February 16, 2020
Recent advances in microwave-assisted organic syntheses
1EnzyMed, a division of Albany Molecular Research Inc, Iowa City, IA 52242, USA. JKrstenansky@enzymed.com
Abstract:
The application of microwaves to organic synthesis is opening up new opportunities for the synthetic chemist by providing new routes not practical by traditional means, such as improved reaction yields, solvent-free reaction conditions or decreasing the time needed for transformations. This is an area of synthesis that is rapidly developing. It is becoming clear that microwave approaches can be developed for most reactions requiring heating. The most interesting developments are those demonstrating the enabling of microwave reactions where traditional methods have failed or give only poor yields. This review intends to point out some of the more interesting papers in this area published over the last year or so, where the microwave method was demonstrated as clearly superior to previously available techniques or a new useful approach was presented.
Related Concept Videos
Radical Chain-Growth Polymerization: Overview
Radical Chain-Growth Polymerization: Mechanism
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation
SN2 Reaction: Mechanism
The presence of the more electronegative halogen in the substrate creates a polarized carbon-halide bond. The halide pulls the electron cloud generating an electrophilic center at the carbon atom. Thus, the carbon atom carries a partial positive charge while the halide has a...
SN2 Reaction: Kinetics
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a reaction.
Cycloaddition Reactions: MO Requirements for Thermal Activation

