[Hydroxyapatite/collagen. Experimental study of its application in facial surgery and report of a case]

A new implant made of purified fibrillar collagen (P.F.C.) and hydroxylapatite particles (HA) (Maxill-HAPR) is tested in canine mandibulae and surrounding tissues so that its integration and its bone-induction capacity can be histologically studied. A clinical case is also reported. The goal of this combined implant is to improve the interface of the HA particles with the host-tissues through the P.F.C. This study shows that P.F.C. is replaced after two months by host fibro-conjunctive tissues. Between 3 and 4 months, ossification areas are observed. After 6 months, the host conjunctive tissue is replaced by bone surrounding the HA particles. P.F.C.-HA implants can be made for replacement or restoration of facial bones not submitted to important forces like the frontal or malar bones.