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Nodular fasciitis: differential considerations and current management strategies
Stephen R Grobmyer1, Jacquelyn A Knapik, Robin M Foss
1Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida, USA. stephen.grobmyer@surgery.ufl.edu
Nodular fasciitis (NF) can mimic soft tissue sarcoma, posing diagnostic challenges. Early recognition and appropriate management are crucial for patients presenting with these soft tissue masses.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Nodular fasciitis (NF) presents as a rapidly growing soft tissue mass.
- Imaging findings of NF can be mistaken for soft tissue sarcoma or desmoid tumors.
- Accurate diagnosis and management of NF can be challenging due to its variable presentation.
Observation:
- Two cases of nodular fasciitis were initially diagnosed as soft tissue sarcoma.
- Case 1: A 46-year-old woman with a chest wall mass misdiagnosed as sarcoma.
- Case 2: A 65-year-old woman with an infraclavicular mass also suspected as sarcoma.
Findings:
- Core biopsy in Case 1 suggested inflammation only.
- Preoperative biopsy in Case 2 suggested NF.
- Both patients underwent surgical excision, confirming nodular fasciitis as the final diagnosis.
Implications:
- These cases underscore the importance of considering NF in the differential diagnosis of soft tissue masses.
- Highlighting clinical challenges in evaluating and managing patients with suspected soft tissue tumors.
- Emphasizing the need for comprehensive diagnostic approaches, including biopsy and histopathological examination, for definitive NF diagnosis.
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