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Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

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Staphylococcal Skin Infections

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Updated: Jun 21, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Community-associated methicillin-resistant Staphylococcus aureus mediastinitis.

Tatjana P Calvano1, David M Ferraro, Vidhya Prakash

  • 1Department of Medicine, San Antonio Military Medical Center, Fort Sam Houston, Texas, USA.

Journal of Clinical Microbiology
|August 7, 2009
PubMed
Summary

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are rising, mainly affecting skin and soft tissues. This report details the first adult case of CA-MRSA mediastinitis, confirmed through laboratory analysis.

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Last Updated: Jun 21, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is an increasing cause of severe infections.
  • CA-MRSA typically manifests as skin and soft tissue infections.

Observation:

  • This study documents the first reported case of CA-MRSA mediastinitis in an adult patient.
  • The infection involved the mediastinum, a critical central chest area.

Findings:

  • Isolates from both blood and mediastinal samples were identified as CA-MRSA.
  • Pulsed-field gel electrophoresis and susceptibility testing confirmed the CA-MRSA identification.

Implications:

  • This case expands the known spectrum of severe infections caused by CA-MRSA.
  • Highlights the need for vigilance in diagnosing invasive CA-MRSA infections beyond typical skin presentations.
  • Suggests potential for CA-MRSA to cause deep-seated infections in immunocompetent adults.