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Validation of US as a first-line diagnostic test for assessment of pediatric ileocolic intussusception
Anastasia L Hryhorczuk1, Peter J Strouse
1Department of Radiology, University of Michigan Health System, Ann Arbor, MI 48109, USA. ahryhorc@med.umich.edu
Insights
Ultrasound (US) is a highly sensitive and specific tool for diagnosing pediatric ileocolic intussusception. This study confirms its value as a primary diagnostic method, showing high accuracy in identifying this condition.
Area of Science:
- Pediatric Radiology
- Gastrointestinal Imaging
- Diagnostic Ultrasound
Background:
- Ultrasound (US) has been a potential primary diagnostic tool for ileocolic intussusception since the early 1980s.
- Our institution has consistently employed US for ileocolic intussusception assessments since 2001.
Purpose of the Study:
- To evaluate the efficacy of ultrasound (US) as a primary diagnostic test for intussusception.
- To analyze a 7-year institutional experience with US for intussusception diagnosis.
Main Methods:
- A retrospective review of 814 US examinations for intussusception in children aged 10 years and younger.
- Classification of cases as true-positive, true-negative, false-positive, or false-negative based on clinical records and radiological reports.
Main Results:
- Overall sensitivity of US was 97.9% and specificity was 97.8%.
- Positive predictive value was 86.6%, and negative predictive value was 99.7%.
- Less than 1% of US studies were nondiagnostic.
Conclusions:
- Ultrasound (US) demonstrates high sensitivity and specificity for detecting ileocolic intussusception.
- US should be considered the first-line imaging modality for evaluating suspected pediatric intussusception.
Background:
From the early 1980s onward, US has been considered a possible primary modality to assess patients for ileocolic intussusception. Since 2001, our institution has routinely used US to assess patients for ileocolic intussusception.
Objective:
We analyzed 7 years of institutional experience to assess the value of US as a primary diagnostic test for intussusception.
Materials And Methods:
This study was IRB-approved. From 1 January 2001 through 16 December 2007 814 US examinations for intussusception were performed in children aged 10 years and younger. Clinical records and radiological reports were reviewed for each patient, and cases were classified as true-positive, true-negative, false-positive, or false-negative.
Results:
Of the 814 US examinations, 112 (13.8%) were interpreted as positive for intussusception, and of these, 96 were confirmed by enema, 1 was confirmed by surgery, and 15 (13.4%) were false-positive. Of the 814 examinations, 700 (85.9%) were interpreted as negative for intussusception, and of these, 698 (99.7%) were true-negative, and 2 were false-negative. Less than 1% of studies were nondiagnostic. The overall sensitivity of US for detecting intussusception was 97.9% and specificity was 97.8%. The positive predictive value of the test was 86.6% and the negative predictive value was 99.7%.
Conclusion:
US is a sensitive and specific test for detecting ileocolic intussusception and should be utilized as a first-line examination for assessment of possible pediatric intussusception.
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