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Induction of leukotriene B4 formation by dialyzer membranes
1Medizinische Klinik Innenstadt, Universität München, FRG.
Biomaterials, Artificial Cells, and Artificial Organs
|January 1, 1990
Abstract:
Interactions between blood and dialysis membranes lead to activation of the 5-lipoxygenase pathway of the arachiodonic acid metabolism during hemodialysis. Newly generated leukotriene B4 (LTB4) may contribute to the multifaceted granulocyte abnormalities of uremic patients.