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Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
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Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Long-term Depression01:05

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Identification of postpartum depression.

Dorothy K Y Sit1, Katherine L Wisner

  • 1Department of Psychiatry, Western Psychiatric Institute and Clinic University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213, USA. sitdk@upmc.edu

Clinical Obstetrics and Gynecology
|August 8, 2009
PubMed
Summary

Postpartum depression (PPD) screening by obstetrician-gynecologists is crucial for early identification. This review covers diagnostic criteria, risk factors, screening tools, and management strategies for PPD.

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Last Updated: Jun 21, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

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Area of Science:

  • Obstetrics and Gynecology
  • Psychiatry
  • Public Health

Background:

  • Postpartum depression (PPD) is a significant medical complication affecting childbearing women.
  • Early identification and management of PPD are essential for maternal well-being.
  • Obstetrician-gynecologists are uniquely positioned for PPD screening during routine postpartum visits.

Purpose of the Study:

  • To review diagnostic criteria and clinical risk factors for postpartum depression.
  • To examine depression screening tools, optimal timing, and acceptability in obstetrical settings.
  • To explore management and treatment options for women with PPD.

Main Methods:

  • Literature review of diagnostic criteria for postpartum depressive disorders.
  • Analysis of clinical risk factors predictive of PPD.
  • Evaluation of depression screening tools, cut-points, timing, and patient acceptability.

Main Results:

  • The study synthesizes information on PPD diagnosis, risk factors, and screening efficacy.
  • It provides insights into the practical application of screening tools in obstetrical care.
  • Management and treatment pathways for positive screens are discussed.

Conclusions:

  • Universal screening for postpartum depression by obstetrician-gynecologists can enhance early detection.
  • Effective management strategies and treatment options are available for PPD.
  • Integrating PPD screening into routine postpartum care is recommended.