Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 21, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

Ipsilateral versus bilateral central neck lymph node dissection in papillary thyroid carcinoma.

Tracy-Ann S Moo1, Ben Umunna, Meredith Kato

  • 1New York Presbyterian Hospital - Cornell, New York, NY, USA. trm9012@nyp.org

Annals of Surgery
|August 8, 2009
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting ncRNA control networks with engineered exosomes to overcome therapy resistance in thyroid cancer.

Critical reviews in oncology/hematology·2026
Same author

The Relationship Between Socioeconomic Status and Emergence Delirium: A Retrospective Cohort Study.

Paediatric anaesthesia·2026
Same author

An ICAM1-Targeting Chimeric Costimulatory Receptor Mimics the Immune Synapse and Enhances Tumor-Specific T-cell Function.

Cancer immunology research·2026
Same author

Distensibility index might predict the risk of developing new onset or worsening dysphagia after anti-reflux surgery.

Surgical endoscopy·2026
Same author

Preoperative MRA for Patients with Retinoblastoma Undergoing Intra-Arterial Chemotherapy.

AJNR. American journal of neuroradiology·2025
Same author

Audiovisual Distraction Increases Success Rates of Sedation-Free Pediatric Magnetic Resonance Imaging.

Paediatric anaesthesia·2025

For papillary thyroid carcinoma (PTC) patients with tumors less than 1 cm, unilateral central neck dissection (CND) is sufficient. Bilateral CND should be considered for larger tumors to manage nodal disease effectively.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Endocrine Surgery

Background:

  • Papillary thyroid carcinoma (PTC) frequently presents with subclinical nodal disease.
  • Nodal metastasis in PTC increases local recurrence rates and impacts radioactive iodine therapy.
  • Prophylactic central neck dissection (CND) is increasingly adopted for PTC management.

Purpose of the Study:

  • To prospectively evaluate the adequacy of unilateral prophylactic central neck dissection (CND) for papillary thyroid carcinoma (PTC).
  • To determine if ipsilateral CND is sufficient for PTC patients, considering potential complications of bilateral CND.

Main Methods:

  • A prospective study involving 116 patients with PTC undergoing total thyroidectomy and prophylactic CND.
  • Separate pathological examination of right and left central neck lymph node basins in 45 patients.

More Related Videos

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach
07:45

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

Published on: November 28, 2025

Related Experiment Videos

Last Updated: Jun 21, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach
07:45

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

Published on: November 28, 2025

  • Analysis of lymph node positivity based on tumor size and location.

    • Main Results:

    • 45% of patients had positive lymph nodes.
    • In patients with lateralized CND, 33% had only ipsilateral positive nodes, and 20% had bilateral positive nodes.
    • Tumor size >1 cm was associated with bilateral positive nodes (31% vs. 0% for tumors <=1 cm, P=0.02).
    • Temporary hypocalcemia occurred in 47%, with no permanent hypocalcemia or permanent recurrent laryngeal nerve injury.

    Conclusions:

    • Ipsilateral CND is adequate for PTC patients with tumors measuring <=1 cm.
    • Bilateral CND should be considered for PTC tumors >1 cm due to a higher likelihood of bilateral nodal involvement.
    • Utilizing tumor size for prophylactic CND strategy could spare approximately one-third of patients from bilateral dissection.