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[Cardiovascular risk in psoriatic arthritis].
Terapevticheskii Arkhiv
|August 12, 2009
Summary
Psoriatic arthritis (PA) patients exhibit elevated cardiovascular risk due to chronic inflammation, leading to early atherosclerosis. This increased risk significantly impacts the long-term prognosis of psoriatic arthritis.
Area of Science:
- Rheumatology
- Cardiology
- Immunology
Context:
- Psoriatic arthritis (PA) is a chronic inflammatory disease.
- Cardiovascular disease is a significant concern in patients with inflammatory conditions.
Purpose:
- To assess cardiovascular risk factors and subclinical atherosclerosis in psoriatic arthritis patients.
- To investigate the association between inflammation activity and cardiovascular risk markers in PA.
Summary:
- Psoriatic arthritis patients demonstrated higher cardiovascular risk compared to controls.
- Elevated total and LDL cholesterol levels correlated with inflammation activity in PA.
- Subclinical atherosclerosis and atherosclerotic plaques were more prevalent in psoriatic arthritis patients.
Impact:
- Chronic immune inflammation in PA contributes to accelerated atherosclerosis.
- High cardiovascular risk is an integral component of psoriatic arthritis, affecting long-term outcomes.
- Findings underscore the need for proactive cardiovascular risk management in psoriatic arthritis patients.
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