Related Experiment Video
Updated: Jun 21, 2026

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
Published on: February 5, 2018
Solid-phase random glycosylation
Károly Agoston1, Lars Kröger, Gyula Dékány
1Department of Chemistry, Faculty of Science, University of Hamburg, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany.
Abstract:
Two different approaches were employed to study solid phase random glycosylations to obtain oligosaccharide libraries. In approach I, Wang resin esters were attached to the acceptors structures. Following their glycosylation and resin cleavage, the peracetylated components of the oligosaccharide libraries were characterized. In approach II, polymer-linked donor components could be employed and processed correspondingly. Approach I proved to be superior regarding yield and versatility of products and also allowed the formation of higher oligomers.
Related Concept Videos
Oligosaccharide Assembly
Multiple sugar molecules that may or may...
Protein Glycosylation
Glycosylation occurs in...
Proteoglycans
Formation of Lipopolysaccharides
Protein Folding Quality Check in the RER

