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Related Concept Videos

Classification of Epithelial Tissues: Simple Epithelium01:30

Classification of Epithelial Tissues: Simple Epithelium

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...
Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
Epithelial Tissues and Their Functions01:23

Epithelial Tissues and Their Functions

Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
Epithelial tissues provide the body's first line of protection from physical, chemical, and...
Classification of Epithelial Tissues: Stratified Epithelium01:29

Classification of Epithelial Tissues: Stratified Epithelium

Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
Classification of Epithelial Tissues: Glandular Epithelium01:20

Classification of Epithelial Tissues: Glandular Epithelium

The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Tissue Membranes01:27

Tissue Membranes

A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial membrane is...

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Related Experiment Video

Updated: Jun 21, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Epithelioid soft tissue tumors.

A Paolo Dei Tos1, Andrew J Wagner, Piergiorgio Modena

  • 1Department of Anatomic Pathology, General Hospital of Treviso, Treviso, Italy. apdeitos@ulss.tv.it

Seminars in Oncology
|August 12, 2009
PubMed
Summary
This summary is machine-generated.

Epithelioid sarcomas, rare tumors mimicking carcinomas, present diagnostic challenges and a high metastasis rate. This review covers their classification and treatment, including novel targeted therapies.

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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

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Last Updated: Jun 21, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

Area of Science:

  • Oncology
  • Pathology
  • Soft Tissue Tumors

Background:

  • Epithelioid neoplasms are typically carcinomas, but some sarcomas exhibit epithelioid morphology and cytokeratin expression.
  • These rare sarcomas present unique diagnostic and therapeutic challenges due to their distinct behavior, including a higher propensity for lymph node metastasis compared to other sarcomas.

Purpose of the Study:

  • To review major categories of epithelioid soft tissue tumors.
  • To discuss clinical data and diagnostic/therapeutic challenges associated with these tumors.
  • To highlight opportunities for investigating novel protein-targeted agents.

Main Methods:

  • Literature review of epithelioid soft tissue tumors.
  • Analysis of clinical data and pathological features.
  • Discussion of current and investigational therapeutic strategies.

Main Results:

  • Epithelioid sarcomas are a distinct group of soft tissue tumors with unique clinicopathological features.
  • These tumors demonstrate a higher rate of lymph node metastasis than other sarcomas.
  • Investigational protein-targeted agents show promise for treating these challenging neoplasms.

Conclusions:

  • Epithelioid sarcomas require careful diagnosis and specialized management.
  • Understanding their unique metastatic behavior is crucial for effective treatment planning.
  • Further research into targeted therapies is essential for improving patient outcomes.