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Published on: December 3, 2011
[Measles outbreak in Barcelona. Clinical and epidemiological characteristics]
Laura Monfort1, David Muñoz, Victoria Trenchs
1Sección de Urgencias, Servicio de Pediatría, Hospital Universitari Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Introduction:
Measles is an acute, highly contagious illness that affects humans, the only natural host. Although effective attenuated virus vaccines exist for this disease, outbreaks continue to occur in susceptible subgroups. From August 2006 to July 2007, an outbreak of measles occurred in the Barcelona (Spain) area, resulting from an imported case. The aim of this study was to describe the clinical and epidemiological characteristics of children with microbiologically confirmed measles diagnosed at our hospital.
Methods:
Retrospective, descriptive study. The clinical histories and emergency records of children diagnosed with measles and evaluated at our hospital during the outbreak were analyzed.
Results:
Of the 130 children with suspected measles evaluated, 99 cases were confirmed by laboratory tests. Median age at diagnosis was 12.4 months (25th-75th percentile: 9.6-14.4 months; 74.6% 6-15 months of age) and 51.4% were boys. Among the total, 23.6% of patients had been vaccinated against measles and 55.3% reported previous contact with a confirmed measles case. The most frequent symptoms/signs were fever (100%; mean evolution 4.3 days (standard deviation [SD]: 2.2 days), rash (82.7%), Koplik's spots (60.2%), and red eyes (59.2%). Complementary tests were performed in 35.7% of children. Most common complications were acute otitis media (20.4%) and pneumonia (15.3%). Among the total, 23.5% of patients were hospitalized for a mean duration of 6.6 days (SD: 3.6 days).
Conclusion:
Geographical mobility facilitates the reappearance of diseases having a low incidence. Infants 6-15 months of age were the patient group most highly affected by the measles outbreak. Most cases were diagnosed with typical signs and symptoms of the infection, but as the outbreak advanced, patients were diagnosed based on less specific symptoms because of the epidemiological context.
Insights
Measles outbreaks continue despite vaccines. This study details a 2006-2007 Barcelona outbreak, finding infants aged 6-15 months were most affected, often presenting with fever and rash.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Measles is a highly contagious viral illness with available vaccines, yet outbreaks persist in vulnerable populations.
- An imported case triggered a measles outbreak in Barcelona, Spain, from August 2006 to July 2007.
- This study aimed to characterize children with confirmed measles during this specific outbreak.
Purpose of the Study:
- To describe the clinical features of children diagnosed with measles.
- To outline the epidemiological characteristics of pediatric measles cases during the outbreak.
- To identify the most affected age groups and common symptoms.
Main Methods:
- A retrospective, descriptive study design was employed.
- Analysis of clinical histories and emergency records of children with confirmed measles.
- Data collected from patients evaluated at a single hospital during the outbreak period.
Main Results:
- 99 confirmed measles cases were identified among 130 suspected cases.
- The median age was 12.4 months, with 74.6% aged 6-15 months; 23.6% had prior vaccination.
- Common symptoms included fever (100%), rash (82.7%), Koplik's spots (60.2%), and conjunctivitis (59.2%). Complications involved otitis media (20.4%) and pneumonia (15.3%).
Conclusions:
- Infants aged 6-15 months were the most impacted demographic during this measles outbreak.
- While initial cases presented with typical symptoms, later diagnoses relied more on epidemiological context due to evolving presentation.
- The study highlights the ongoing risk of measles resurgence, even with vaccination, facilitated by global travel.
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