Infection prevention in the intensive care unit
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Updated: Jun 21, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Mary C Barsanti1, Keith F Woeltje
1Division of Infectious Diseases, Department of Internal Medicine,Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8051, St. Louis, MO 63110, USA.
Abstract:
Hospital-acquired infections have profound social, economic, and personal costs to patients in the intensive care unit (ICU). Numerous risk factors, such as poor nutrition and hyperglycemia, directly involve patients. Meanwhile, hand hygiene, environmental cleaning, and appropriate hospital staffing can impact ICU infection rates. A multidirectional approach-including continuing staff education, minimizing risk factors, and implementing guidelines established by national committees-is necessary to decrease infections such as catheter-related bloodstream infections, urinary tract infections, ventilator-associated pneumonia, and Clostridium difficile. Infection-control committees can assist in implementing policies. This is an active area of research and we anticipate continued advancements to improve patient care.
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