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Related Experiment Videos

Ruminant pestivirus infection in pigs.

B Liess1, V Moennig

  • 1Institute of Virology, Division of Clinical Virology, Hanover Veterinary School, Federal Republic of Germany.

Revue Scientifique Et Technique (International Office of Epizootics)
|March 1, 1990
PubMed
Summary

Ruminant pestiviruses, like bovine virus diarrhoea virus (BVDV), can infect pigs, potentially impacting hog cholera surveillance. Differentiating these viruses is crucial for accurate diagnostics and disease control programs.

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[80 years of the Society of Friends of the University of Veterinary Medicine Hannover].

DTW. Deutsche tierarztliche Wochenschrift·2007

Area of Science:

  • Veterinary Virology
  • Animal Health
  • Infectious Diseases

Background:

  • Ruminant pestivirus infections, particularly bovine virus diarrhoea virus (BVDV), are globally prevalent in pigs.
  • Infection prevalence is influenced by cattle contact, pig age, and serological test strain homology.
  • Sources beyond cattle, such as contaminated vaccines and fetal calf serum, contribute to BVDV spread in swine.

Purpose of the Study:

  • To highlight the importance of differentiating ruminant pestiviruses from hog cholera virus (HCV) in pigs.
  • To discuss the antigenic relationships and in vitro host range of pestiviruses.
  • To explore the potential for BVDV to interfere with hog cholera eradication programs.

Main Methods:

  • Review of existing literature on pestivirus infections in pigs.

Related Experiment Videos

  • Analysis of monoclonal antibody capabilities for differentiating pestiviruses.
  • Examination of in vitro host range studies of BVDV strains.
  • Main Results:

    • BVDV strains can infect pigs, presenting clinical signs similar to hog cholera.
    • Monoclonal antibodies can distinguish between HCV and ruminant pestiviruses.
    • Multipotent BVDV strains show broader cell culture adaptability, including porcine cells.

    Conclusions:

    • Distinguishing BVDV from HCV in pigs is essential for accurate diagnosis and surveillance.
    • Understanding viral attachment mechanisms may aid in differentiating infections.
    • While not immediately requiring control measures, BVDV infections can compromise hog cholera eradication efforts.