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Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
Potential bias in ophthalmic pharmaceutical clinical trials
1John J Pershing Veterans' Administration Medical Center, Poplar Bluff, Missouri, USA. paul.varner@va.gov
Clinical Ophthalmology (Auckland, N.Z.)
|August 12, 2009
Abstract:
To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the study design of various pharmaceutical ophthalmic clinical trials was completed. Discrepancies as a result of study shortcomings may explain observed differences between reported ophthalmic trial data and observed clinical results.
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