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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: Jun 21, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Comparative biometric study between plateau iris configuration and primary open angle glaucoma with narrow angle.

Alberto Diniz Filho¹, Sebastião Cronemberger, Rafael Vidal Mérula

¹School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. adinizfilho@yahoo.com.br

Arquivos Brasileiros De Oftalmologia

|August 12, 2009

Summary

Plateau iris configuration eyes have significantly shorter axial length and thicker central corneal thickness compared to primary open angle glaucoma with narrow angle eyes. These biometric differences are key for understanding glaucoma risk.

Related Experiment Videos

Last Updated: Jun 21, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Area of Science:

Ophthalmology
Biometry
Glaucomatology

Background:

Plateau iris configuration (PIC) is an anatomical variation that can predispose individuals to angle-closure glaucoma.
Primary open-angle glaucoma (POAG) with narrow angles presents a distinct clinical challenge.
Understanding the biometric differences between these conditions is crucial for accurate diagnosis and management.

Purpose of the Study:

To conduct a biometric investigation comparing eyes with plateau iris configuration (PIC) and primary open-angle glaucoma (POAG) with narrow angles.
To identify specific ocular parameters that differentiate these two conditions.

Main Methods:

A comparative case series study involving 11 patients with PIC (20 eyes) and 27 patients with POAG and narrow angles (45 eyes).
Key biometric measurements included corneal curvature, central corneal thickness, anterior chamber depth, lens thickness (LT), axial length (AL), LT/AL ratio, lens position (LP), and relative lens position (RLP).

Main Results:

PIC eyes showed statistically significantly higher central corneal thickness (P=0.010) and shorter axial length (P=0.003) compared to POAG with narrow angle eyes.
No statistically significant differences were observed in corneal curvature (P=0.090), anterior chamber depth (P=0.078), LT (P=0.975), LT/AL ratio (P=0.569), LP (P=0.164), or RLP (P=0.348).

Conclusions:

Eyes with plateau iris configuration exhibit significantly shorter axial length and greater central corneal thickness than those with primary open-angle glaucoma and narrow angles.
These distinct biometric findings contribute to the understanding of ocular anatomy in glaucoma and may aid in risk stratification.