Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent developments in blood cell labeling research.

S C Srivastava1, R F Straub, G E Meinken

  • 1Medical Department, Brookhaven National Laboratory, Upton, New York.

Acta Radiologica. Supplementum
|January 1, 1990
PubMed
Summary

New methods for labeling blood cells, including red blood cells, leukocytes, and platelets, using technetium-99m (99mTc) and monoclonal antibodies, are discussed, highlighting advantages and challenges in this diagnostic imaging field.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characteristics of Conventional and Microwave Sintered Iron Ore Preform.

Materials (Basel, Switzerland)·2022
Same author

Negative ion formation in electrospray mass spectrometry.

Journal of the American Society for Mass Spectrometry·2013
Same author

Production of actinomycin-D by the mutant of a new isolate of Streptomyces sindenensis.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2013
Same author

Production of Sn-117m in the BR2 high-flux reactor.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2009
Same author

Occurrence and distribution of hexachlorocyclohexane isomers in vegetation samples from a contaminated area.

Chemosphere·2008
Same author

Surgical technologist: an emerging breed?

The National medical journal of India·2006

Area of Science:

  • Nuclear medicine and hematology
  • Biomedical imaging and diagnostics

Background:

  • Accurate blood cell labeling is crucial for various diagnostic and research applications.
  • Existing labeling techniques have limitations in efficiency, specificity, and safety.

Purpose of the Study:

  • To present recent advancements in blood cell labeling methodologies.
  • To evaluate novel in vitro labeling techniques for red blood cells, leukocytes, and platelets.
  • To explore the application of monoclonal antibody techniques in platelet labeling.

Main Methods:

  • Development and application of an in vitro method for technetium-99m (99mTc) labeling of red blood cells.
  • Adaptation of 99mTc labeling for leukocytes and platelets.
  • Utilizing monoclonal antibody technology for specific platelet labeling.

Related Experiment Videos

Main Results:

  • Detailed examination of the advantages and disadvantages of the presented labeling techniques.
  • Analysis based on current mechanistic understanding of cell labeling processes.
  • Identification of unresolved issues and areas requiring further investigation.

Conclusions:

  • Significant progress has been made in blood cell labeling methodology.
  • The monoclonal antibody approach shows promise for enhanced platelet labeling.
  • Further research is needed to overcome existing challenges and optimize labeling protocols.