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Updated: Jun 21, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

Published on: October 26, 2017

[Biomarker in pulmonary diseases].

A Gillissen¹, V Wiechmann, U R Jürgens

¹Robert-Koch-Klinik, Thoraxzentrum des Klinikums St. Georg, Nikolai-Rumjanzew-Strasse 100, Leipzig. www.rkk-leipzig.de

Pneumologie (Stuttgart, Germany)

|August 12, 2009

Summary

Biological markers aid in diagnosing and managing airway and lung diseases. While some, like procalcitonin and nitric oxide, are clinically valuable, new breath analysis methods show promise for future pulmonary diagnostics.

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Last Updated: Jun 21, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

Published on: October 26, 2017

Area of Science:

Pulmonary Medicine
Biomarker Discovery
Respiratory Diagnostics

Context:

Biological markers are crucial for diagnosing, predicting, and monitoring airway and lung diseases.
Established biomarkers like procalcitonin, alpha-1-antitrypsin, D-Dimers, and exhaled nitric oxide have proven clinical utility.
Current research focuses on novel biomarkers in exhaled breath condensate and air.

Purpose:

To review recent data on the clinical usefulness of biomarkers in non-malignant pulmonary diseases.
To highlight the supportive role of biomarkers alongside routine diagnostic methods.
To explore emerging techniques for biomarker detection in respiratory conditions.

Summary:

The article examines the application of biological markers in diagnosing and managing non-malignant pulmonary diseases.
It discusses established biomarkers and their roles, alongside newer approaches analyzing exhaled breath.
Biomarkers offer valuable support for conventional diagnostic procedures.

Impact:

Enhances understanding of biomarker utility in respiratory medicine.
Informs clinicians about the potential of novel diagnostic approaches.
Supports the development of more precise and personalized pulmonary disease management strategies.