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Be precise! The need to consider the mechanisms for CEP17 copy number changes in breast cancer

Giuseppe Viale1

  • 1Division of Pathology, European Institute of Oncology, Università degli Studi di Milano, Milan, Italy. giuseppe.viale@ieo.it

The Journal of Pathology
|August 12, 2009
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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...