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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
4D vs 2D ultrasound-guided amniocentesis
Gabriele Tonni1, Gabriele Centini, Lucia Rosignoli
1Division of Obstetrics and Gynecology, Guastalla Civil Hospital, AUSL Reggio Emilia, Reggio Emilia, Italy.
Journal of Clinical Ultrasound : JCU
|August 12, 2009
Summary
Four-dimensional (4D) ultrasonography (US) did not demonstrate superiority over standard 2D US for guiding amniocentesis. This advanced technique did not improve needle placement or reduce the number of insertions needed during the procedure.
Area of Science:
- Medical Imaging
- Obstetrics and Gynecology
- Fetal Medicine
Background:
- Amniocentesis is a common prenatal diagnostic procedure.
- Standard 2D ultrasonography (US) is routinely used for guidance.
- Advancements in US technology, such as 4D US, may offer improved visualization.
Purpose of the Study:
- To compare the effectiveness of 4D US versus 2D US in guiding amniocentesis.
- To evaluate the impact of 4D US on needle placement, number of insertions, and procedure duration.
Main Methods:
- A prospective study comparing 100 4D US-guided amniocenteses with 100 2D US-guided amniocenteses.
- All procedures were performed by trainees under expert supervision.
- Outcomes assessed included needle placement accuracy, number of needle insertions, and procedure time.
Main Results:
- No statistically significant differences were found between 4D and 2D US guidance for amniocentesis.
- Procedure time was slightly longer with 4D US, but not statistically significant.
- Needle insertion rates were similar, with a slight trend favoring 2D US.
Conclusions:
- 4D US, despite real-time multiplanar visualization, offered no significant advantage over 2D US for routine midtrimester amniocentesis.
- The effectiveness of 4D US in reducing needle insertions has not been demonstrated.
- Further research may be needed to explore potential benefits of 4D US in specific scenarios.

