[Plant as bioreactor].

Area of Science:

• Biotechnology
• Molecular Biology
• Plant Sciences

Context:

• Plant-based systems offer a scalable and cost-effective alternative for heterogenous protein expression.
• Traditional methods face challenges in yield, purification, and cost for complex proteins.

Purpose:

• To review and analyze diverse plant bioreactor systems for protein expression.
• To highlight recent technological developments and innovations in the field.
• To discuss future perspectives and challenges based on practical experience.

Summary:

• This review examines various plant expression platforms, including viral, bacterial, and yeast-based systems, for recombinant protein production.
• Key advancements in genetic engineering, metabolic pathway optimization, and downstream processing are discussed.
• The integration of different expression strategies and their potential for industrial-scale manufacturing is explored.

Impact:

• Provides a comprehensive overview of plant bioreactors for researchers and industry professionals.
• Identifies promising avenues for improving protein yield, quality, and economic viability.
• Facilitates the development of novel therapeutic proteins and industrial enzymes using plant-based systems.