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[Study of syndrome differentiation factor of gouty arthritis with blood stasis syndrome based on connection number]
1Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. drlibin88@yahoo.com.cn
Insights
Pain, tophi, and skin changes are key indicators for gouty arthritis with blood stasis syndrome. This study used mathematical analysis to identify primary diagnostic factors for improved clinical guidance.
Area of Science:
- Rheumatology
- Traditional Chinese Medicine
- Mathematical Modeling
Context:
- Gouty arthritis, a metabolic disorder, is often associated with blood stasis syndrome in Traditional Chinese Medicine.
- Accurate identification of syndrome factors is crucial for effective diagnosis and treatment of gouty arthritis.
- Existing diagnostic methods may benefit from quantitative approaches to refine syndrome differentiation.
Purpose:
- To identify and prioritize the key syndrome factors of gouty arthritis with blood stasis syndrome using set pair analysis and connection number.
- To provide a mathematical basis for guiding the diagnosis of gouty arthritis with blood stasis syndrome.
- To enhance the precision of TCM-based diagnosis for gouty arthritis.
Summary:
- A study analyzed 70 patients with gouty arthritis and blood stasis syndrome using the connection number method.
- Five primary syndrome factors were identified with dialectics connection values (DCV) above 0.5: pain (0.858), sublingual varices/palatal mucosa signs (0.773), tophus (0.723), varicose veins/telangiectasis (0.700), and dry skin (0.612).
- These factors, particularly pain and specific physical signs, are highlighted as significant indicators.
Impact:
- The findings offer a quantitative approach to diagnosing gouty arthritis with blood stasis syndrome.
- Identified key factors can guide clinicians in prioritizing diagnostic elements.
- This mathematical method may improve the consistency and accuracy of TCM syndrome differentiation in rheumatology.
Objective:
To find the related syndrome factors of gouty arthritis with blood stasis syndrome by mathematical methods of set pair analysis and connection number so as to guide the diagnosis.
Methods:
Seventy gouty arthritis patients diagnosed with blood stasis syndrome were analyzed according to priority by the method of connection number. Syndrome factors of gouty arthritis with blood stasis syndrome were selected according to the numerical values of dialectics connection value (DCV).
Results:
In the nine observed items, the DCVs of five syndrome factors were above 0.5. These five factors were pain (0.858 0), sublingual varices and positive signs (varices and dark purple color) for palatal mucosa (0.773 1), tophus (0.723 0), varicose veins and telangiectasis (0.700 9), and squamous and dry skin (0.612 3). The DCVs of the other factors were below 0.5.
Conclusion:
The main factor 1 is pain; factor 2 is sublingual varices and positive signs (varices and dark purple color) for palatal mucosa; factor 3 is tophus; factor 4 is varicose veins and telangiectasis; factor 5 is dry skin. The others are secondary factors.
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