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Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Mesenteric panniculitis: various presentations and treatment regimens
1Department of Gastroenterology & Hepatology, Rafik Hariri University Hospital, Beirut 2034-7304, Lebanon. iyadissa71@gmail.com
Abstract:
Mesenteric panniculitis is a rare, benign and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery of the small intestine and colon. The specific etiology of the disease is unknown. The diagnosis is suggested by computed tomography and is usually confirmed by surgical biopsies. Treatment is empirical and based on a few selected drugs. Surgical resection is sometimes attempted for definitive therapy, although the surgical approach is often limited. We report two cases of mesenteric panniculitis with two different presentations and subsequently varying treatment regimens. Adequate response was obtained in both patients. We present details of these cases as well as a literature review to compare various presentations, etiologies and potential treatment modalities.
Insights
Mesenteric panniculitis, a rare inflammatory disease, presents unique diagnostic and treatment challenges. This report details two cases, highlighting varied approaches and successful outcomes for this uncommon condition.
Area of Science:
- Gastroenterology and Surgical Pathology
- Abdominal Imaging and Interventional Radiology
- Inflammatory and Fibrotic Diseases
Background:
- Mesenteric panniculitis is a rare, benign, chronic inflammatory condition affecting the mesentery.
- Its etiology remains unknown, posing diagnostic and therapeutic challenges.
- Diagnosis typically involves computed tomography (CT) and surgical biopsies.
Observation:
- Two distinct cases of mesenteric panniculitis with varied clinical presentations were observed.
- Different treatment regimens were employed based on individual patient presentations.
- Computed tomography (CT) and surgical biopsies were crucial for diagnosis.
Findings:
- Both patients demonstrated an adequate response to their respective, individualized treatment strategies.
- The study compares diverse presentations, potential etiologies, and therapeutic options for mesenteric panniculitis.
- Surgical resection, while sometimes attempted, has limitations in definitive treatment.
Implications:
- This case series provides insights into managing mesenteric panniculitis with varied approaches.
- Understanding different presentations aids in tailoring empirical treatment regimens.
- Further research may elucidate the etiology and optimize treatment protocols for this rare disease.
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