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Differential induction of transcription for glucocorticoid-responsive genes in cultured rat hepatocytes

V L Nebes1, D DeFranco, S M Morris

  • 1Department of Microbiology, Biochemistry and Molecular Biology, University of Pittsburgh, PA 15261.

Biochemical and Biophysical Research Communications
|January 25, 1990
PubMed

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Cell Specific Gene Expression01:58

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...