Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 21, 2026

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays
07:51

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays

Published on: October 19, 2016

Form-function relations in cone-tipped stimulating microelectrodes.

Steve Yaeli1, Einat Binyamin, Shy Shoham

  • 1Faculty of Biomedical Engineering, Technion - Israel Institute of Technology Israel.

Frontiers in Neuroengineering
|August 15, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermal bioeffects considerations for transcranial focused ultrasound associated neurodegeneration.

Brain stimulation·2026
Same author

Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation.

Nature neuroscience·2026
Same author

Bessel beam side lobe suppression via non-degenerate two-photon excitation.

Biomedical optics express·2026
Same author

Temporal sequence geometry enables odor recognition and generalization.

bioRxiv : the preprint server for biology·2026
Same author

CaBLAM: a high-contrast bioluminescent Ca<sup>2+</sup> indicator derived from an engineered Oplophorus gracilirostris luciferase.

Nature methods·2025
Same author

Brain-wide hemodynamic responses to precise transcranial ultrasound neuromodulation.

Brain stimulation·2025
Same journal

In vivo comparison of the charge densities required to evoke motor responses using novel annular penetrating microelectrodes.

Frontiers in neuroengineering·2015
Same journal

SET: a pupil detection method using sinusoidal approximation.

Frontiers in neuroengineering·2015
Same journal

The chronic challenge-new vistas on long-term multisite contacts to the central nervous system.

Frontiers in neuroengineering·2015
Same journal

High frequency switched-mode stimulation can evoke post synaptic responses in cerebellar principal neurons.

Frontiers in neuroengineering·2015
Same journal

NeuroPG: open source software for optical pattern generation and data acquisition.

Frontiers in neuroengineering·2015
Same journal

A low-cost programmable pulse generator for physiology and behavior.

Frontiers in neuroengineering·2015
See all related articles

This study reveals how cone-tipped tungsten microelectrode geometry impacts neuro-stimulation. Tip angle is crucial for charge injection capacity, while impedance relates to surface area, and corrosion resistance is independent of size.

Area of Science:

  • Neuroscience
  • Bioengineering
  • Materials Science

Background:

  • Metal microelectrodes are vital tools in neuroscience research for stimulation and recording.
  • Understanding the relationship between microelectrode geometry and function is crucial for optimizing neuro-stimulation applications.

Purpose of the Study:

  • To investigate the impact of tip geometry on the electrical properties and performance of cone-tipped tungsten microelectrodes.
  • To establish quantitative relationships between microelectrode geometry and key functional parameters.

Main Methods:

  • A combined approach using experimental measurements and physical finite element simulations.
  • Analysis of 1-kHz impedance, current distribution, charge injection capacity, and critical corrosion current.
Keywords:
cone-tippedcritical current densitydeep brain stimulationfinite elements modelmicroelectrodes

More Related Videos

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications
09:35

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Published on: October 4, 2016

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

Related Experiment Videos

Last Updated: Jun 21, 2026

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays
07:51

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays

Published on: October 19, 2016

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications
09:35

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Published on: October 4, 2016

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

Main Results:

  • Established an inverse square-root relationship between microelectrode impedance and exposed tip surface area.
  • Demonstrated that tip angle significantly influences current distribution and charge injection capacity.
  • Found that critical current for corrosion onset is independent of tip surface area in sharp microelectrodes.

Conclusions:

  • Microelectrode tip geometry, particularly tip angle and surface area, critically dictates electrical properties and stimulation capabilities.
  • The findings provide essential data for designing optimized stimulating microelectrodes for neuroscience applications.
  • Corrosion behavior is predictable and not influenced by surface area for sharp tungsten microelectrodes.