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Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
Published on: September 1, 2015
Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in AIDS patients with
Somnuek Sungkanuparph1, Scott G Filler, Ploenchan Chetchotisakd
1Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand. rasuy@mahidol.ac.th
Abstract:
A prospective multicenter study of cryptococcal immune reconstitution inflammatory syndrome (IRIS) was conducted as a substudy of the Bacteriology and Mycology Study Group 3-01. Of 101 AIDS patients with cryptococcal meningitis who received highly active antiretroviral therapy (HAART), 13 experienced cryptococcal IRIS. No association between the timing of HAART initiation and the diagnosis of IRIS was identified. Increased baseline serum cryptococcal antigen (CrAg) titer was a risk factor for cryptococcal IRIS.
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