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Updated: Jun 21, 2026

Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm
Published on: April 28, 2016
Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure
S Kovac1, G Möddel, J Reinholz
1Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. stjepana@uni-muenster.de
Objective:
The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure.
Methods:
In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other.
Results:
Language lateralization and memory lateralization were positively correlated (r=0.34, P<0.01). Correlations differed depending on the presence and type of lesion (chi(2)=7.98, P<0.05). LIs correlated significantly higher (z=2.82, P<0.05) in patients with cortical dysplasia (n=41, r=0.61, P<0.01) compared with the group without lesions (n=90, r=0.16, P>0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P<0.01) and language (P<0.01) LIs were higher in right- compared with left-sided lesions.
Conclusion:
Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI.
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