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Related Concept Videos

Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...

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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

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Published on: February 17, 2018

Stress cardiomyopathy.

Yoshihiro J Akashi1, Holger M Nef, Helge Möllmann

  • 1Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki-city, Kanagawa-prefecture, Japan. johnny@marianna-u.ac.jp

Annual Review of Medicine
|August 19, 2009
PubMed
Summary
This summary is machine-generated.

Stress cardiomyopathy, also known as takotsubo cardiomyopathy, affects many, particularly elderly women. This review summarizes current research on its causes, symptoms, and potential treatments.

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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Area of Science:

  • Cardiology
  • Cardiovascular Medicine
  • Pathophysiology

Background:

  • Stress cardiomyopathy (SC), or takotsubo cardiomyopathy, is increasingly recognized globally, predominantly in elderly women.
  • SC mimics acute myocardial infarction but lacks coronary artery obstruction, featuring left ventricular apical ballooning.
  • It is a significant cause of acute heart failure, arrhythmias, and ventricular rupture.

Purpose of the Study:

  • To provide a comprehensive review of stress cardiomyopathy.
  • To synthesize findings from basic science (bench) to clinical practice (bedside) and vice versa.
  • To discuss proposed pathogenic mechanisms and current understanding of the condition.

Main Methods:

  • Literature review of studies on stress cardiomyopathy.
  • Synthesis of research findings from bench-to-bedside and bedside-to-bench perspectives.
  • Summary of proposed etiological mechanisms, including catecholamine cardiotoxicity and neurogenic stunned myocardium.

Main Results:

  • Stress cardiomyopathy presents with symptoms similar to myocardial infarction but without coronary artery blockages.
  • Left ventricular apical ballooning is a hallmark characteristic of the condition.
  • The disease is a recognized cause of severe cardiac events like heart failure and arrhythmias.

Conclusions:

  • Stress cardiomyopathy is a significant clinical entity requiring further research into its precise onset mechanisms.
  • Understanding the interplay between catecholamine cardiotoxicity and neurogenic stunned myocardium is crucial.
  • Continued research from basic science to clinical application is essential for managing takotsubo cardiomyopathy.