Related Experiment Video
Updated: Jun 20, 2026

06:31
Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
The strip patch test--indication in occupational dermatology demonstrated with a case history
Heinrich Dickel1, Nina Scola, Peter Altmeyer
1Department of Dermatology and Allergology, Division of Allergology, Occupational and Environmental Dermatology, St. Josef-Hospital, Ruhr-University, Bochum, Germany. dickel@derma.de
Summary
The strip patch test (SPT) can diagnose allergic contact dermatitis missed by standard patch tests. This method confirmed a potassium dichromate allergy, impacting a patient's disability and pension.
Area of Science:
- Occupational Dermatology
- Allergic Contact Dermatitis
- Diagnostic Immunology
Background:
- Repeat patch testing is common in occupational dermatology for expert opinions.
- Discrepancies in patch test results can affect insurance claims and disability assessments.
- Standard patch tests may yield false-negative results for weak sensitizers or those with poor skin penetration.
Observation:
- A 30-year-old industrial mechanic with a history of potassium dichromate sensitization faced challenges with standard patch tests.
- Initial patch tests in 2005 confirmed sensitization, but subsequent tests in 2006 and 2008 were negative.
- The strip patch test (SPT), performed in a standardized manner, successfully reconfirmed the potassium dichromate sensitization.
Findings:
- The strip patch test (SPT) identified a sensitization to potassium dichromate that standard patch tests missed.
- This confirmed allergy was crucial for the patient's occupational disease claim and insurance evaluation.
- The SPT results led to an adjustment in the patient's disability severity and established pension entitlement.
Implications:
- The strip patch test (SPT) is a valuable tool for diagnosing allergic contact dermatitis when standard patch tests are negative.
- Accurate diagnosis through SPT can significantly impact legal and insurance outcomes for patients with occupational skin diseases.
- Standardized SPT protocols are essential for reliable detection of weak sensitizations in occupational dermatology.
Related Concept Videos
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

