Related Experiment Video

Updated: Jun 20, 2026

Human Ovarian Surface Epithelium Organoids as a Platform to Study Tissue Regeneration
07:37

Human Ovarian Surface Epithelium Organoids as a Platform to Study Tissue Regeneration

Published on: August 16, 2024

Stem cell support of oogenesis in the human

Gulcin Abban, Joshua Johnson

    Human Reproduction (Oxford, England)
    |August 19, 2009
    PubMed
    Summary

    New research shows that female germline stem cells (FGSCs) from adult mice can produce offspring. This finding opens new avenues for understanding ovarian physiology and treating reproductive dysfunction.

    More Related Videos

    Evaluation of Stem Cell Properties in Human Ovarian Carcinoma Cells Using Multi and Single Cell-based Spheres Assays08:39

    Evaluation of Stem Cell Properties in Human Ovarian Carcinoma Cells Using Multi and Single Cell-based Spheres Assays

    Published on: January 3, 2015

    Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture09:50

    Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture

    Published on: October 24, 2025

    Related Concept Videos

    Oogenesis02:07

    Oogenesis

    In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
    Oogenesis01:22

    Oogenesis

    Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
    Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
    Folliculogenesis01:20

    Folliculogenesis

    Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
    Maintenance of the ES Cell State01:14

    Maintenance of the ES Cell State

    The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...
    Zygotic Development And Stem Cell Formation01:10

    Zygotic Development And Stem Cell Formation

    The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
    Hormonal Control of the Ovarian Cycle01:30

    Hormonal Control of the Ovarian Cycle

    The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
    Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...