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Updated: Jun 20, 2026
CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
CO(2) laser therapy in Tis and T1 glottic cancer: indications and results
Lucio Rucci1, Paolo Romagnoli, Jacopo Scala
1Department of Oto-Neuro-Ophthalmological Surgical Sciences, Division of Otorhinolaryngology-Head and Neck Surgery, University of Florence, Florence, Italy. lucio.rucci@unifi.it
Background:
Laser cordectomy for glottic cancer is still hampered by recurrence, which is more frequent upon anterior commissure (AC) involvement. Analysis of results may be a step to improve the efficacy of this therapy for early glottic cancer.
Methods:
In all, 81 patients who underwent surgery with CO(2) laser for Tis and T1, AC0 to AC2 glottic carcinoma were followed up to 55 months.
Results:
The incidence of recurrence increased significantly with T and AC classifications. The disease-free interval decreased with increasing T and AC classifications and with increasing severity of histology, but only the AC classification appeared significant. Recurrences occurred in 5 of 35 patients upon type I and type II cordectomy, in 16 of 24 patients upon type V cordectomy, and never upon type III and IV cordectomy.
Conclusions:
Type I to type IV cordectomy, when indicated, can achieve radical treatment of most T1 glottic cancer. Type V cordectomy requires that any suspicion of cartilage invasion, even microscopic, be excluded.
