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Updated: Jun 20, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Papillary thyroid carcinoma presenting with upper respiratory tract obstruction and pulmonary metastases
Youssef Al-Tonbary1, Khaled Zalata, Rasha El-Ashry
1Pediatric Hematology and Oncology Unit, Mansoura University Children's Hospital, Mansoura University, Mansoura, Egypt. ytonbary@gmail.com
Background:
Thyroid cancer is rare in children especially before the age of 10 years. Upper airway obstruction and pulmonary infiltration are rare manifestations of such tumor.
Methods:
An 8-year-old school girl was admitted to Mansoura University Children's Hospital for a papillary thyroid carcinoma manifested by severe upper respiratory tract obstruction. CT scan of the chest revealed multiple miliary shadows in both lungs.
Results:
Total thyroidectomy was performed and pathological examination confirmed the diagnosis of papillary carcinoma of the thyroid gland. The patient received ablative dose of Iodine 131 and replacement therapy of L-thyroxine.
Conclusion:
Thyroid cancer, although rare, should be considered for differential diagnosis of upper airway obstruction and pulmonary metastases.
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