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Updated: Jun 20, 2026

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate
Published on: September 9, 2011
Cutaneous gamma/delta T-cell lymphoma
Richard Koch1, Elaine S Jaffe, Christian Mensing
1Eduard-Arning Clinic for Dermatology and Allergology Asklepios Klinik St. Georg, Lohmühlenstraße 5, Hamburg, Germany. ri.koch@asklepios.com
None:
Only 40 cases of primary cutaneous gamma/delta T-cell lymphoma (GD-TCL) have been described. GD-TCL was included as a provisional entity in the WHO-EORTC classification of cutaneous lymphomas in 2005. GD-TCL often failed to respond to polychemotherapy and radiation therapy and have a poor prognosis with a mean survival of only 15 months. We present a patient treated with surgery, immunomodulatory therapy, and polychemotherapy. He then received hematopoietic stem cell transplantation and has been in complete remission since. Allogeneic stem cell transplantation appears to be a promising therapeutic option for aggressive and generally fatal lymphomas like GD-TCL.
