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Updated: Jun 20, 2026

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
Published on: November 1, 2012
Contraction band necrosis in two ecstasy abusers: a latent lethal lesion associated with ecstasy
Yi Shao Hua1, Ren Liang, Liu Liang
1Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Abstract:
Cardiotoxicity associated with ecstasy has been reported in recent years but is very rare. We described 2 lethal cases associated with Ecstasy use. One whole tablet of ecstasy in one case and a half-tablet ecstasy in another case led to lethal effect, but death was not simply attributed to a lethal intoxication. Severe myocardial contraction band necrosis was observed in these 2 cases as revealed by the histopathologic examination. Focal interstitial infiltration of lymphocyte and monocyte around myocardial lesions in case one was also found. The results suggest that contraction band necrosis could be induced by ecstasy and is a potential lethal lesion in some cases.
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