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Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
Vitamin D: bone and beyond, rationale and recommendations for supplementation
Sarah A Stechschulte1, Robert S Kirsner, Daniel G Federman
1Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Fla, USA.
The American Journal of Medicine
|August 25, 2009
Summary
Maintaining adequate vitamin D levels is crucial for overall health, impacting bone health, immunity, and reducing risks of chronic diseases. Supplementation offers a safe and effective way to prevent and correct vitamin D deficiency.
Area of Science:
- Endocrinology
- Nutritional Science
- Preventive Medicine
Background:
- Vitamin D deficiency is a global health concern affecting a significant portion of the population.
- Adequate vitamin D status is essential for numerous physiological functions beyond bone health.
- Emerging research highlights vitamin D's role in reducing risks for various chronic conditions.
Purpose of the Study:
- To emphasize the importance of optimizing vitamin D status in primary care.
- To discuss the benefits of vitamin D beyond skeletal health.
- To evaluate safe and effective strategies for improving vitamin D levels.
Main Methods:
- Review of current scientific literature on vitamin D's health implications.
- Analysis of the risks and benefits of different vitamin D repletion strategies.
- Assessment of vitamin D's role in preventing bone disease, falls, and chronic illnesses.
Main Results:
- Vitamin D sufficiency is linked to reduced risk of bone disease, falls, pain, autoimmune disorders, cancer, heart disease, and cognitive decline.
- Increased sun exposure, while a source of vitamin D, carries risks of photoaging and skin cancer.
- Vitamin D supplementation is identified as a safe and effective method for correcting deficiency and insufficiency.
Conclusions:
- Optimizing vitamin D levels is a key component of modern primary care.
- Supplementation is the recommended strategy for achieving adequate vitamin D status, avoiding risks associated with sun exposure.
- Ensuring sufficient vitamin D benefits overall health and may reduce the incidence of several serious health conditions.
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